Drawn from the same murky well of Hollywood ethical ambiguity that gave us 'Thank You for Smoking' and last year's 'Up in the Air,' 'Love & Other Drugs' audaciously defines its slick anti-hero protagonist as beyond reproach. The filmmakers are clearly banking on the allure of nude sex scenes between Jake Gyllenhaal and Anne Hathaway to attract audiences, but the love story (and sex scenes) don't amount to much. Grade: C.

