For many of us, weight loss doesn’t look like a six-month miracle transformation. Years of trying new diets with no success, having no energy to exercise, stalled progress, and sliding backward after a minor bout of “cheating” are all very common problems.
Thankfully, you don’t have to put up with fighting an uphill battle to maintain just a little progress or seeing no gains at all.
There are natural weight loss supplements that actually work, and we’ve done hours of research to find them. Among the best weight loss supplements overall is PhenQ.
Want to know more? Keep reading to see the other brands on our list of the best weight loss supplements of 2024.
Best Weight Loss Supplements Top Picks
- PhenQ - Best weight loss supplements overall
- KetoCharge - Best for the keto diet
- Phen24 - Best for 24-hour weight loss
- PrimeShred - Best weight loss supplements for men
- CalmLean - Best stim-free weight loss supplement
- Brutal Force ACUT - Best Anavar alternative
- Brutal Force WINCUT - Best Winstrol alternative
- Trimtone - Best belly fat burner
- Instant Knockout Cut - Best for muscle support
- Zotrim - Best appetite suppressant
- Powher - Best weight loss supplements for women
- Transparent Labs RECOMP - Best for thermogenesis
The best weight loss supplements contain helpful ingredients and tackle weight loss from several angles, including boosting metabolism and lowering cravings. Find out which weight loss supplement is right for you in our review of the top 12 on the market.
1. PhenQ - Best Weight Loss Supplements Overall
Pros
- Utilizes premium ingredients
- May support cognitive function and balance your mood
- 60-day money-back guarantee
Cons
- Formula doesn’t disclose ingredient dosages
Who Is PhenQ Best For?
PhenQ is for you if you want to rev up your metabolism and support your cardiovascular, metabolic, and brain health all at the same time.
The key ingredient in PhenQ is a-Lacys Reset, a compound that has been shown to reduce body fat and weight while increasing muscle mass. Capsimax is PhenQ’s other proprietary formula. This is less irritating to your digestive system than regular capsaicin, so you may experience its fat-burning benefits with minimal side effects.
For older users, Capsaicin may also protect against age-related health problems involving memory and cardiovascular health [1].
Ingredients
- a-Lacys reset
- Capsimax powder
- Caffeine anhydrous
- Chromium picolinate
- L-carnitine fumarate
- Nopal
Dosage
- Two tablets per day
- One in the morning and one in the evening
Summary
PhenQ lets you attack excess fat by lowering appetite, improving metabolism, and helping you get better workout results with more fat burned.
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2. KetoCharge - Best for the Keto Diet
Pros
- Supports the state of ketosis
- Electrolytes for proper hydration
- 60-day money-back guarantee
Cons
- Only for keto enthusiasts
Who Is KetoCharge Best For?
KetoCharge is one of the best diet pills if you want to go keto or prefer a cyclic keto diet, but dread the infamous “keto flu.” The formula helps to regulate functions that may be suppressed in the ketogenic diet, especially due to its extremely low-carb nature [2].
Ingredients
- Sodium beta-hydroxybutyrate
- Magnesium beta-hydroxybutyrate
- Calcium beta-hydroxybutyrate
Dosage
- Two capsules per day
- First thing in the morning with a glass of water
Summary
KetoCharge is the only keto-related weight loss formula on our list, but we think it’s the best of its kind in the market. It not only supports the process of ketosis, but it also helps you retain electrolytes, which are normally lost in keto.
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3. Phen24 - Best for 24-Hour Weight Loss
Pros
- Includes a day and night formula
- May help prevent midnight snacking
- Free shipping worldwide
Cons
- May interact with antidepressants
Who Is Phen24 Best For?
Phen24 is one of the best weight loss supplements for continued fat burning, whether you’re up or asleep. It includes cayenne in the Day formula and choline in the Night capsules, both of which enhance fat burning and may boost energy.
Yet another ingredient in Phen24 is L-phenylalanine, part of the Day formula that may help prevent cravings [3].
Ingredients
Daytime
- Ashwagandha
- Guarana
- Caffeine
- Cayenne powder
Nighttime
- Chromium
- Griffonia extract
- Theanine
Dosage
- One daytime capsule before breakfast
- Two nighttime capsules before evening meal
Summary
Phen24 features Day and Night formulas so you may benefit from enhanced fat burning all day, without the stimulant effects at night, alongside reduced cravings.
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4. PrimeShred - Best Weight Loss Supplements for Men
Pros
- Includes B vitamins for natural energy production
- Rhodiola and tyrosine to keep you motivated
- Fat-burning ingredients
Cons
- May be overstimulating if you take ADHD meds or nootropics
Who Is PrimeShred Best For?
PrimeShred is for any man who wants to lose stubborn fat and achieve their weight loss goals. One of the key ingredients in PrimeShred is green tea extract. Green tea extract may support the rate of fat burning, lower cholesterol, and increase energy [4].
PrimeShred also contains caffeine, theanine, and tyrosine, which may work together to boost athletic performance. This combination may improve movement accuracy during exercise, helping you to finish your training session or game and enjoy yourself while doing it [5].
Ingredients
- BioPerine
- Green tea extract
- Vitamin B complex
- Rhodiola rosea root
- Green coffee bean
- L-tyrosine
- L-theanine
- Cayenne pepper seeds
- DMAE
- Caffeine anhydrous
Dosage
- Three capsules per day
- Twenty minutes before food
Summary
PrimeShred offers the best weight loss supplements for men, with powerful stimulants that may help you burn fat and boost your athletic performance.
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5. CalmLean - Best Stim-Free Weight Loss Supplement
Pros
- Does not contain caffeine
- May enhance blood sugar control
- Cardiovascular and metabolic benefits of capsaicin
Cons
- You may not feel as energized with CalmLean
Who Is CalmLean Best For?
If you want to lose weight without feeling jittery from caffeine, CalmLean might be the perfect choice for you. CalmLean contains ForsLean, a natural extract from the Coleus forskohlii plant. ForsLean may help you burn fat and build lean muscle by boosting your metabolism and insulin sensitivity. It can also support your bone health and mood. [6]
Ingredients
- ForsLean
- Capsicum annuum (chilli) extract
- Chromium
- Black pepper extract
Dosage
- Two capsules per day
Summary
CalmLean switches up stimulants for the metabolic health-promoting effects of Coleus forskohlii and capsicum.
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6. Brutal Force ACUT - Best Anavar Alternative
Pros
- Focuses on protecting muscle mass
- Supports energy production during exercise
- 100-day money back guarantee
- 24/7 customer support
Cons
- Contains soy and dairy products
Who Is Brutal Force ACUT Best For?
Brutal Force ACUT is best for men and women who know that effective weight loss is all about losing body fat while supporting, or even increasing, muscle.
The main ingredients in Brutal Force ACUT are soy and whey protein, alongside BCAAs for targeted muscle support [7]. ElevATP is a “minor,” yet still active, ingredient in Brutal Force ACUT. It’s a blend of peat and apple extracts, rich in minerals such as magnesium and calcium; trace elements; and antioxidants [8].
Not only may more energy production help you lose weight and feel great, but so can more muscle mass. Your muscles are the most energy-demanding tissue type when they’re at work, and they even use energy to maintain themselves at rest [9].
Ingredients
- Soy protein isolate
- Whey protein isolate
- BCAAs
- Wild yam powder
- ElevATP
- Silica and magnesium stearate
Dosage
- Three capsules per day, 15 minutes after workout
Summary
Brutal Force ACUT tops our list of the best weight loss supplements around. It may help you boost your muscle mass and energy, so you can enjoy long-term fat loss results and an overall improvement to your health and fitness.
Check out the best prices for Brutal Force ACUT
7. Brutal Force WINCUT - Best Winstrol Alternative
Pros
- Boosts fat burning for energy
- May support mental focus and performance
- Low risk alternative to Winstrol
- Caffeine-free formula
Cons
- Taking your supplement 45 minutes before a workout may be inconvenient
Who Is Brutal Force WINCUT Best For?
Brutal Force WINCUT is best for you if you’re losing fat while building muscle, especially if athletic performance is a top priority. One of the key ingredients in WINCUT is choline, which may protect your cells’ structural integrity and supports nerve cell communication (an essential part of sports performance) [10].
Ingredients
- Acetyl-l-carnitine
- Choline
- DMAE
- Wild yam powder
- Safflower oil
Dosage
- Two capsules per day 45 minutes before workout
Summary
WINCUT could do wonders for your energy levels during exercise, allowing you to burn fat by building muscle
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8. Trimtone - Best Belly Fat Burner
Pros
- Unique natural fat burner for long-term results
- Contains glucomannan to relieve cravings
- 100-day money-back guarantee
- One serving per day
Cons
- Glucomannan may reduce nutrient absorption
Who Is Trimtone Best For?
Trimtone offers the best weight loss supplements for burning fat, including stubborn abdominal fat. One ingredient in Trimtone is grains of paradise, a unique addition among supplements for weight management. It’s best to combine Trimtone with a healthy diet and exercise plan, but research does show that grains of paradise alone may reduce body fat [11].
Ingredients
- Caffeine anhydrous
- Green coffee
- Green tea extract
- Grains of paradise
- Konjac fiber (glucomannan)
Dosage
- One dose per day
Summary
Trimtone not only contains your classic metabolism boosters such as caffeine and green tea extract, but also grains of paradise, which supports you long-term by reactivating brown fat.
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9. Instant Knockout Cut - Best for Muscle Support
Pros
- Antioxidants that may protect your muscles
- Black pepper to enhance supplement absorption
- Same-day shipping available
Cons
- Glucomannan may interfere with medications
Who Is Instant Knockout Cut Best For?
Instant Knockout Cut is best for active users, especially people who love the daily gym grind. It utilizes a four-fold approach to weight loss, focusing on calorie control, appetite control, thermogenic boost, and a well-balanced diet.
Green tea extract is among Instant Knockout Cut’s antioxidants. The antioxidant properties of green tea extract may partially protect against muscle loss while you’re losing weight, or during days you don’t exercise [12].
Ingredients
- Cayenne pepper
- Vitamin D3, B6, and B12
- Green tea extract
- Glucomannan
Dosage
- Four capsules per day
- Don’t take the last dose less than five hours before bed
Summary
Instant Knockout Cut keeps your muscles safe from tissue breakdown during weight loss, thanks to its antioxidant properties.
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10. Zotrim - Best Appetite Suppressant
Pros
- Clinically studied formula
- Five clinical trials support Zotrim’s formula
- Potent appetite suppressant formula
- Includes caffeine, vitamin B3, and vitamin B6 for energy
Cons
- Not for the caffeine-sensitive
Who Is Zotrim Best For?
Zotrim may offer some of the best weight loss supplements if you have a family history of obesity and struggle to lose weight. The main ingredients, a combination of yerba mate, guarana, and damiana, may reduce body fat accumulation [13]. It’s also designed to help make you less likely to overeat by promoting healthy blood sugar levels.
Ingredients
- Yerba mate
- Guarana
- Damiana
- Vitamin B3
- Vitamin B6
- Caffeine
Dosage
- Take two capsules of Zotrim before eating
Summary
Zotrim is an evidence-based formula that may work by reducing tendencies to overeat and store fat. It also contains caffeine, which not only adds a quick energy boost, but may also have appetite suppressant properties.
Check out the best prices for Zotrim
11. Powher - Best Weight Loss Supplements for Women
Pros
- Includes glucomannan to fight cravings
- Contains caffeine to boost energy and performance
- No-questions-asked money-back guarantee for 90 days
- Provides hormonal support for older women
Cons
- Glucomannan may not be suitable if you take prescription meds
Who Is Powher Best For?
Powher is for women struggling with a slow metabolism, especially if they’re older and experience low energy levels every day.
Besides the weight loss staples of glucomannan, choline, and caffeine, Powher contains selenium. As your thyroid hormones control your metabolism, and selenium is a critical thyroid mineral, selenium may indirectly shrink your waistline and melt unwanted body fat [14].
Ingredients
- Glucomannan
- Choline
- Caffeine
- Chromium
- Selenium
Dosage
- Two capsules three times daily
Summary
Powher is one of the best diet pills for women as it packs a metabolism-boosting punch for women who want to burn more calories.
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12. Transparent Labs RECOMP - Best for Thermogenesis
Pros
- Avoids artificial colors and preservatives
- Lists ingredients transparently
- Increases energy expenditure
- Boosts fat oxidation
- Uses components backed by research
Cons
- Formula may appear “boring”
Who Is Transparent Labs RECOMP for?
Transparent Labs RECOMP uses a simple, but effective formula that boosts your metabolism and thermogenesis. Thermogenesis is the process of heat production in your body, which helps you burn fat and stay warm. The supplement contains only natural ingredients that enhance thermogenesis, such as green tea, cayenne pepper, and forskolin.
Transparent Labs Ingredients
- Caffeine
- Green Tea Extract
- 5-HTP
- Forslean
- Capsimax
- Bioperine
Transparent Labs Dosage
- 2 capsules with 8-10 ounces of water, twice daily
- 30-60 minutes before meals
Summary
If you’re looking for a high-quality fat burner for better thermo, Transparent Labs RECOMP is a great choice. It will help you increase your thermogenesis and lose weight faster and easier.
Check the best deals for Transparent Labs RECOMP
What Are Weight Loss Supplements?
The best weight loss supplements may help you lose weight more effectively by supporting your metabolism, energy, appetite, and fat burning. You may get more out of your weight loss journey by adding a weight loss supplement to your daily routine. This way, you may reach your fat loss goals sooner.
Types of Weight Loss Supplements That Actually Work
Each brand that made it to our best weight loss supplements list has its own benefits. From the usual energy-boosting perks to the fancy herbal complexes with nootropics, each formula is designed to make weight loss easier for you.
Appetite Suppressants
Appetite suppressants help control cravings and reduce hunger pangs. They limit the number of hunger signals that go to the brain.
Thermogenic Fat Burners
Fat burners increase your metabolism and help your body burn fat more effectively. They often utilize thermogenesis to increase calorie burn, which is the generation of energy as heat.
Carb Blockers
Carb blockers prevent the breakdown of complex carbohydrates, reducing their contribution to your caloric intake.
Fat Blockers
Fat blockers may reduce the digestion and absorption of fats. Glucomannan can, in a way, act as a carb and fat blocker because it slows the absorption of both nutrient types into your bloodstream.
Metabolism Boosters
Metabolism boosters enhance your cells’ ability to produce energy, so you may burn fat while enjoying a better quality of life and exercise performance.
Prescription Weight Loss Supplements
In addition to over-the-counter weight loss supplements, there are also prescription options available. These include Orlistat, which prevents the intestines from absorbing unwanted fat; Contrave, which regulates hunger and reward mechanisms in the brain; and Phentermine, a weight loss drug that suppresses appetite.
It’s important to remember that these prescription products generally have more severe side effects compared to the best weight loss supplements we found.
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Common Ingredients in OTC Weight Loss Supplements
The best weight loss supplements that actually work often share similar ingredients and with good reason. These compounds have a decent amount of research to back their claims regarding fat loss, appetite suppression, and thermogenesis.
Garcinia Cambogia Extract
Garcinia cambogia extract blocks the creation of new fat deposits and curbs appetite. It may also control cholesterol and blood glucose levels.
Raspberry Ketones
Raspberry ketones may boost fat metabolism and increase the release of adiponectin, which regulates blood glucose levels. They have the potential to help those struggling with obesity.
Green Coffee Bean Extract
Green coffee bean extract contains chlorogenic acid, a natural fat burner that acts as an appetite suppressant and activates thermogenesis.
Glucomannan
Glucomannan may help you break the habit of overeating by expanding to form a coating in your digestive tract. This makes you feel full or satisfied with a smaller meal.
Green Tea Extract
Green tea extract has been linked to improved appetite suppression and fat burning. It contains caffeine, which provides energy and stimulates fat-burning hormones in the body.
Conjugated Linoleic Acid (CLA)
CLA is a naturally occurring fatty acid that may help reduce total fat mass, body fat percentage, and torso fat [16].
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Frequently Asked Questions
Here are some of the most common questions customers ask when looking for the best weight loss supplements that actually work.
Do the Best Weight Loss Supplements Have Any Side Effects?
Some ingredients in the best weight loss supplements, such as caffeine, may be overstimulating; others, such as glucomannan, could reduce drug and nutrient absorption.
Are Weight Loss Supplements FDA Approved?
Dietary supplements do not necessarily require FDA approval, as they often carry “wellness” claims instead of specific therapeutic claims.
How Much Do Good Weight Loss Capsules Cost?
The best weight loss supplements are great value for money, and we found that they generally cost $2 or less per dose. If you buy packages that give you several months’ supply, your daily dose may cost $1-1.50.
Best Weight Loss Supplements: Final Thoughts
You deserve to feel confident and healthy in your own body. You need weight loss supplements backed by science and proven to work; brands that can help you gain muscle, speed up your metabolism, increase your energy, and control your hunger.
PhenQ is one of those brands. It doesn’t just target one aspect of weight loss, but tackles it from multiple angles. It may help you eat less, workout more, and burn fat faster.
Achieve your goals and enjoy a better quality of life. Try PhenQ today and see the difference for yourself.
References
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- Rabast, U et al. “Loss of weight, sodium and water in obese persons consuming a high- or low-carbohydrate diet.” Annals of nutrition & metabolism vol. 25,6 (1981): 341-9. doi:10.1159/000176515
- Hitsman, Brian et al. “Effects of acute tyrosine/phenylalanine depletion on the selective processing of smoking-related cues and the relative value of cigarettes in smokers.” Psychopharmacology vol. 196,4 (2008): 611-21. doi:10.1007/s00213-007-0995-5
- Roberts, Justin D et al. “The Impact of Decaffeinated Green Tea Extract on Fat Oxidation, Body Composition and Cardio-Metabolic Health in Overweight, Recreationally Active Individuals.” Nutrients vol. 13,3 764. 26 Feb. 2021, doi:10.3390/nu13030764
- Zaragoza, Javier et al. “Effects of acute caffeine, theanine and tyrosine supplementation on mental and physical performance in athletes.” Journal of the International Society of Sports Nutrition vol. 16,1 56. 26 Nov. 2019, doi:10.1186/s12970-019-0326-3
- Loftus, Hayley L et al. “Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial.” Nutrients vol. 7,11 9508-22. 17 Nov. 2015, doi:10.3390/nu7115483
- Paul, Greg, and Garry J Mendelson. “Evidence Supports the Use of Soy Protein to Promote Cardiometabolic Health and Muscle Development.” Journal of the American College of Nutrition vol. 34 Suppl 1 (2015): 56-9. doi:10.1080/07315724.2015.1080531
- Reyes-Izquierdo T, Nemzer B, Argumedo R, Shu C, Huynh L, Pietrzkowski Z. “Effect of the dietary supplement ElevATP on blood ATP level: An acute pilot clinical study.” Journal of Aging Research and Clinical Practice. 2 (2013): 178–84.
- Hamilton, Marc T et al. “The Necessity of Active Muscle Metabolism for Healthy Aging: Muscular Activity Throughout the Entire Day.” Progress in molecular biology and translational science vol. 155 (2018): 53-68. doi:10.1016/bs.pmbts.2017.12.014
- Michel, Vera et al. “The impact of choline availability on muscle lipid metabolism.” Food & function vol. 2,1 (2011): 53-62. doi:10.1039/c0fo00069h
- Yoneshiro, Takeshi et al. “Prolonged Treatment with Grains of Paradise (Aframomum melegueta) Extract Recruits Adaptive Thermogenesis and Reduces Body Fat in Humans with Low Brown Fat Activity.” Journal of nutritional science and vitaminology vol. 67,2 (2021): 99-104. doi:10.3177/jnsv.67.99
- Alway, Stephen E et al. “Green tea extract attenuates muscle loss and improves muscle function during disuse, but fails to improve muscle recovery following unloading in aged rats.” Journal of applied physiology (Bethesda, Md. : 1985) vol. 118,3 (2015): 319-30. doi:10.1152/japplphysiol.00674.2014
- Santos, Juliana C et al. “Effects of yerba maté, a plant extract formulation ("YGD") and resveratrol in 3T3-L1 adipogenesis.” Molecules (Basel, Switzerland) vol. 19,10 16909-24. 21 Oct. 2014, doi:10.3390/molecules191016909
- Navas-Carretero, Santiago et al. “Frequent consumption of selenium-enriched chicken meat by adults causes weight loss and maintains their antioxidant status.” Biological trace element research vol. 143,1 (2011): 8-19. doi:10.1007/s12011-010-8831-x
- Devaraj, Ramya Devi et al. “Health-promoting effects of konjac glucomannan and its practical applications: A critical review.” International journal of biological macromolecules vol. 126 (2019): 273-281. doi:10.1016/j.ijbiomac.2018.12.203
- Esmaeili Shahmirzadi, Fatemeh et al. “The Effect of Conjugated Linoleic Acid Supplementation on Body Composition, Serum Insulin and Leptin in Obese Adults.” Archives of Iranian medicine vol. 22,5 255-261. 1 May. 2019
